Not Available

We apologise but the Imperial Brands Science website isn’t available in your geographic location. Please visit our corporate site to find out more about the science we’re undertaking and the innovations we’re exploring.

Imperial Brands Science

Research Archive

Explore scientific data on both our Next Generation and traditional tobacco portfolios. Use the filters below to narrow things down, or simply search via keyword. Scroll down to explore scientific data.

Category

Scientific Assessment Area

Format Types

Date

A Survey of Aerosol Exposure Systems Relative to the Analysis of Cytotoxicity – A CORESTA Perspective

View

Reduced Levels of HPHCs in HT Aerosol Translates to Reduced In Vitro (Geno)Toxicological Outcomes

View

Multi-endpoint analysis of human 3D airway epithelium following repeated exposure to whole electronic vapor product aerosol or cigarette smoke

View

Imperial Brands’ Nicotine Pouches – A Promising Tobacco Harm Reduction Product for Adult Smokers

View

Assessing the Relative In Vitro Genotoxic Potential of E-Liquids and their Aerosols – the ToxTracker and Aneugen Clastogen Evaluation Assay

View

Multi-Endpoint Analysis of Human 3D Airway Epithelium Following Repeated Expsoure to Whole Vape Aerosol or Cigarette Smoke

View

An Interlaboratory In Vitro Aerosol Exposure System Reference Study

View

Human Lung Tissue Exposure to Acute Vape Aerosol Results in Minimal Cellular and Transcriptomic Responses Compared to Combustible Cigarettes

View

An In Vitro Genotoxicity Assessment for Next Generation Nicotine Delivery Products – Industrial Genotoxicology Group (IGG) Virtual AM 2020

View

Reduced Developmental Toxicity Potential of Non-Combusted Products Compared to Cigarettes – Screening with Human Induced Pluripotent Stem Cells

View

Collecting E‐Cigarette Aerosols for In Vitro Applications: A Survey of the Biomedical Literature and Opportunities to Increase the Value of Submerged Cell Culture‐based Assessments

View

What is Nicotine? (Infographic)

View

Perception of the Relative Harm of Vapes Compared to Cigarettes Amongst US Adults from 2013 to 2016: Analysis of the PATH Study Data

View

A Comparative In Vitro Toxicity Assessment of Vaping E-liquids and Aerosols with Tobacco Cigarette Smoke

View

Beyond Smoke: Talking Tobacco Harm Reduction Infographic

View

Workshop Recommendations for Use of In Vitro Assay Data for Tobacco Product Evaluation: Phase 1 – Genotoxicity

View

blu – The Science of Something Better

View

Aerosol Concentration Variations in a Room During Use of an E-cigarette

View

Why Flavours Play an Important Role in Vaping

View

Vaping and Public Health

View

The Science of Nicotine and Vaping

View

E-liquids and Product Standards

View

Vaping is not a Gateway to Smoking

View

Vaping and Dual Use

View

Flavours – Something Better is Something Different

View

Toxicant Exposure – Vaping vs Smoking

View

The Science of “Passive Vaping”

View

An Introduction to the Science of Vaping

View

Nicotine Salts Can Help Adult Smokers Move Toward Vaping

View

Glasgow 90-Day Clinical Vaping Study

View

Lab Tests Suggest Human Lung Tissue Unimpacted by Vapour

View

Lab Tests Suggest Vapour Does Not Disrupt Endothelial Cell Migration

View

Vapour – Shows No Evidence of Damage to Lung Cells

View

Nicotine Salts Help More Adult Smokers Transition to Vaping

View

Snus – The Original Reduced Harm Product

View

Heated Tobacco – The Anatomy of Something Better

View

Introducing Tobacco-Free Oral Nicotine Delivery

View

Vapour – The Anatomy of Something Better

View

NGP Flavours – Something Better is Something Different

View

Chemical Composition and In Vitro Toxicity Profile of a Pod-Based E-Cigarette Aerosol Compared to Cigarette Smoke

View

ST20: Responsible Practice in EVP Product Stewardship

View

An Inter-Laboratory Comparison for a Urinary Acrolein Biomarker

View

Analysis of the Effect of Multiple Testing in Assessing Tobacco Product Differences

View

Physical characteristics of handmade premium cigars : specifications and consequences of specifications

View

An in-vitro approach to EVP toxicity testing

View

Nicotine Reduction and Consumer Perception – A Scientific Approach for Quantifying Possible Impact of LNC

View

Nicotine Salts Help More Adult Smokers Transition to Vaping

View

NGPs Induce Lower Biological Activity than Cigarettes Using BioMAP® System of Human Primary Cell Based Co-Cultures

View

Which Parameters are Suitable to Evaluate EVP Puffing Behaviour?

View

Method for Analysis of Volatile Organic Compounds in EVP Aerosol Based on Proton Transfer Reaction Mass Spectrometry

View

Estimation of EVP Aerosol Yields based on Puff Duration

View

Consistency of blu EVP Nicotine Delivery According to the AFNOR Standard

View

Chemical Composition of blu Pod-System EVP Aerosols – A Quantitative Comparison with Conventional Cigarette Smoke

View

Chemical Characterisation of Aerosol Emissions from a Prototype Heated Tobacco Product

View

Real-time Analysis of EVP Aerosol Constituents Using PTR-MS

View

Indoor Air Quality and Exhaled Breath Composition After Use of Nicotine Delivery Products

View

Experimental Method to Determine Concentration of Nicotine in Exhaled Breath and Retention Rate Following EVP Use

View

Smoking Reduction and Cessation Associated with the Three-Month Provision to Smokers of a Refillable Tank-Style E-Cigarette

View

Perceptions of the Relative Harm of Electronic Cigarettes Compared with Smoking in the USA

View

Analysis of the Data Variability in the Australian Benchmark Study 2000-2001

View

Misperception of EVP Harm Growing Among American Adults, 2013-2015

View

EVPs: An Assessment of the So-Called ‘Gateway Effect’ Based on Product Classification

View

Changing Patterns of First EVP Flavour Used and Current Flavors Used by 20,836 Adult Frequent EVP Users in the USA

View

[UPDATE] Perceptions of the Relative Harm of Electronic Cigarettes Compared with Smoking in the USA

View

Parameters Influencing Bystander Exposure to Nicotine in the Indoor Ambient Air During Use of an EVP

View

Modelling of the Effect of Indoor Intermittent Emissions Produced by Electronic Cigarette Users on Exposure of Bystanders

View

Indoor Air Quality and Surface Deposition Assessment following Use of an Open System E-Cigarette

View

Electronic Cigarettes and Indoor Air Quality: A Simple Approach to Modeling Potential Bystander Exposures to Nicotine

View

Characterisation of Spatial and Temporal Dispersion Differences Between Exhaled EVP Vapour and Cigarette Smoke

View

Bystander Exposure to Exhaled EVP Vapour Assessment of Nicotine in Ambient Air Using Modelling & Experimental Approach

View

An Assessment of Nicotine Levels on Office Surfaces Before and After Use of EVPs

View

An Assessment of Indoor Air Quality Before, During and After Unrestricted Use of EVPs in a Small Room

View

An Assessment of Indoor Air Quality Before, During and After Unrestricted Use of EVPs in a Small Room

View

NGPs Predicted to Have No Potential to Induce Developmental Toxicity in the DevTOX QuickPredict Assay

View

The Use of Genomic Allergen Rapid Detection (GARD) Assays to Predict the Respiratory and Skin Sensitising Potential of E-liquids

View

E-Liquids – An Assessment of Dermal Irritancy Potential

View

Analytical Method to Model Human Mouth Level Transfer of Ingredients from Snus

View

Snus: A Compelling Harm Reduction Alternative to Cigarettes

View

Human Mouth-Level Transfer Rate of Menthol, 1.8-cineole and Nicotine from Swedish Pouched Snus

View

Use of Human 3D Bronchial Tissue to Study the Effects of Cigarette Smoke and EVP Aerosol on a Range of Cellular Endpoints

View

Toxicological Comparison of Cigarette Smoke and EVP Aerosol Using a 3D In Vitro Human Respiratory Model

View

The In Vitro Assessment of Respiratory Sensitisation Potential of E-Liquids

View

Influence of Vaping Topography on the Retention Rate of Nicotine

View

High Content Screening in NHBE Cells Shows Reduced Biological Activity of Flavoured E-liquids, Compared to Cigarette Smoke

View

EVPs Induce Lower Biological Responses than Cigarettes – Toxicity Comparison of Aerosol Exposure to Human Bronchial Tissue

View

A Comparison of In Vitro Toxicity Following Repeated Whole Aerosol Exposure to Human Bronchial Tissue for 4 Weeks

View

Cardiovascular and Pulmonary Function Endpoints and Other Effects – EVP vs. Cigarettes in Adult Smokers

View

NGP vs. Cigarettes Comparison of In Vitro Cell Migration in the Scratch Wound Assay

View

Reductions in BoE to HPHCs Following Partial or Complete Substitution of Cigarettes with EVPs

View

Clinical Study Evaluating the Reduction in HPHCs Following Partial or Complete Substitution of Cigarettes with EVPs

View

Evaluation of the Safety Profile of an EVP Used for Two Years by Smokers in a Real-Life Setting

View

Biomarkers of Exposure and Cardiovascular & Pulmonary Function Endpoints in Adult Smokers Using EVPs

View

A Randomised, Parallel Group Study to Evaluate the Safety Profile of an EVP Over 12 Weeks

View

Toxicological Comparison of Cigarette Smoke and NGP Aerosol Bubbled Extracts Using High Content Screening

View

NGP Aerosol Induces Lower Biological Activity than Cigarettes – Comparison of Aerosol Bubbled Extracts

View

NGP Aerosol Bubbled Extracts Show Little to No Effect in High Content Screening Endpoints Compared to Smoke

View

Use of In Vitro Biomarkers From Relevant Primary Cell Systems to Assess the Effects of Experimental and Commercial E-liquid

View

Use of High Content Screening (HCS) in Human Primary Lung Cells to Assess E-liquids

View

Use of Cell Media Nicotine Concentration to Predict Cells Surface Deposited Nicotine in Transwells After Smoke Aerosol Exposure

View

QRA Indicates Reduced Risk Potential for Carcinogenic and Non-carcinogenic Effects of NGP Aerosol Compared to Smoke

View

Pre-Clinical Assessment of a Dual-Temperature Operated Heated Tobacco Device

View

NGPs Induce Lower Biological Activity Than Cigarettes – Comparison of Aerosol Chemistry and In Vitro Toxicity

View

Influence of Vaping Topography on the Retention Rate of Nicotine Following Use of EVP

View

Assessing Changes In Biomarkers Of Effect In Smokers Who Switch To A Closed System EVP

View

Clinical Study Evaluating the PK Profiles of Cigarettes and EVPs with Nicotine Salt Formulations in US Adult Smokers

View

Viral Infection and Nicotine Conversion to Nornicotine in the Next Generation

View

Using a Structural Model based on a Class of Generalised Covariance Criteria, to Explore the Generation Process of Smoke Compounds

View

Use of Molecular Markers Related to Quality Improvement of Tobacco Plant

View

Use of Human Derived Cell Lines to Increase the Biological Relevance of Cigarette Condensate, Non-Tobacco Materials and E-liquids Testing

View

TSNAs in Tobacco and Smoke – PLS Regression for Prediction of Smoke Contents According to Chemical and Physical Characteristics

View

Tobacco Smoke – Chemical and Physical Properties and Toxicity

View

Tobacco Cultivars Evolution in France (1989-2006) and Impact to the Raw Matter

View

Tobacco Characteristics – AMES test

View

Tobacco Breeding Program of Bergerac Tobacco Institute – Methods, Results and Future Prospects

View

The UK Smoke Constituents Testing Study – Summary of Results and Comparison with Other Studies

View

The Regulation and Governance of Residues of Plant Protection Products

View

The PVY Collaborative Experiment (1996-2002) – A Global Synthesis of Results

View

The Protection of Tobacco Varieties with the UPOV System in EU

View

The Influence of Cigarette Design on the Ageing of Carbon Filters

View

The Food and Drug Administration Predictive Toxicology Roadmap and its Implementation

View

The European Tobacco Product Directive and E-cigarette Compliance – a Test Method for Drop Testing of E-liquid Bottles

View

The Effect of Charcoal Filters on Gas Vapour Phase In Vitro Toxicity Tested in Different Air and Liquid Interface Exposure Systems

View

The Application of In Vitro Toxicity Testing in 21st Century (TT21C) for Next Generation Products

View

Targeted Mutation Breeding as a Tool for Tobacco Crop Improvement

View

Strategies to Assess the Biological Properties of Tobacco Smoke

View

Smoke Analysis of Fine-Cut Tobacco (Part 3)

View

Simple and Reliable Method for the Quantification of Proteins in Tobacco

View

Sensory Quality Control by Electronic Nose in Manufacturing Plants

View

Seed Quality Management as a Component of Tobacco Identity Preservation

View

RNA-SEQ Analysis of Orobanche Resistance in Tobacco

View

Responsible Practice in E-Vapour Products (EVP) Product Stewardship

View

Responsible Practice in E-Vapour Products (EVP) Product Stewardship (2)

View

Resistances to the Tobacco Cyst Nematode Complex in Nicotianae

View

Recent Improvements in In Vitro Models Need to be Supported with Refinements in Dosimetry to Enable Possible Future In Vivo Data Extrapolation

View

Real-time Gas Phase Puff-by-Puff

View

Rapid and Sensitive Method to Analyse β-carbolines, Norharman and Harman in Cigarette Smoke

View

Quantitative Risk Assessment (QRA) vs. the Whole Story

View

Prospects for Orobanche Control in Tobacco

View

Prediction of a Biological and a Chemical Variable According to the Tobacco’s Chemical and Physical Characteristics

View

Potential Use of HMA Mutants to Reduce Cadmium Translocation from Root to Leaf in Tobacco

View

Potential Changes of TSNA Composition in Stored Tobacco Powder

View

Patenting Plants – New Challenges

View

Overview of In Vitro Methods to Assess Electronic Nicotine Delivery Systems Based on TT21C Principles

View

Nitrogen Compounds on Mainstream Smoke and Tobacco Precursors

View

Near-infrared Spectroscopy and Pattern Recognition as Screening Methods for Classification of Commercial Tobacco Blends

View

Mutagenicity of Cigarette Smoke Vapour Phase in the AMES Test

View

Modeling of Cigarette Smoke Constituents – From Intense to Less Intense Smoking Regime

View

Methodologies for the Detection and Chemical Characterisation of Particles Released from Cigarette Filters

View

Mechanisms of Transfer of Ammonia in Smoke from Ammonium Compounds in Tobacco

View

Lowering Nicotine Levels in Tobacco Products

View

Investigation of Filter Temperatures and Desorption of Volatiles from Carbon Filters Under Different Smoking Regimes

View

Influence of the Origin of the Cigarette Paper Cellulose on the Chemical Composition of the Smoke and In Vitro Toxicity Test

View

Influence of Cigarette Paper and Filter Ventilaton on Hoffman Analytes

View

Influence of Cigarette Designs and Smoking Regimes on Vapour Phase Yields

View

In Vitro Tests with Fresh Cigarette Smoke – Effects of Charcoal Filters on Whole Smoke and Vapour Phase Mutagenicity and Genotoxicity

View

In Vitro Cytotoxicity of Cigarette Mainstream Smoke. Evaluation of Different Cell Exposure Methods

View

Impact of PVYN Infection on Burley Cigarette Smoke Condensate Properties – An Assessment of the Protection Conferred by the VA Gene

View

IMB Response to UK Science and Technology Committee Enquiry on E-cigarettes

View

How Representative of Human Smoking Behaviour Would New Alternative Smoking Regimes Be

View

Hoffmann Analytes and Cigarette Smoke In Vitro Toxicity – Revisited

View

Hoffmann Analytes – Influence of Cigarette Paper and Filter Ventilation

View

High Throughput Puff-By-Puff Quantification of Smoke Analysis

View

HCN and Tobacco Precursors

View

Hard Science as a Basis for Effective Regulations

View

Handmade Premium Cigar Smoke Emissions Limitations Related to TNCO Determination Variability

View

Further Investigation of Temperatures and Adsorption-Desorption of Volatile Compounds in Carbon Filters Under Different Smoking Regimes

View

Further Data on Cigarette Temperatures and Related Issues

View

Free Radicals in Mainstream Cigarette Smoke Methodology and Influencing Parameters

View

Fingerprints of Tobacco Smoke Precursors by Comprehensive GCxGC

View

Fine-Cut Tobacco Annual TNCO Study using a Monitor Tobacco

View

Fast and Simple Method for the Determination of Urinary 1-Hydroxypyrene

View

Factors Influencing the Formation of Tobacco-Specific Nitrosamines in French Air-Cured Tobaccos in Trials and at the Farm Level

View

Evolutionary Pathways of Potato Virus Y

View

Evaluation of Tobaccos Grown Under Organic Cultural Practices

View

Effects of Filter Ventilation and Activated Carbon Filters on Cigarette Smoke Constituent Uptake

View

Effect of Sugar Content on Acetaldehyde Yield in Cigarette Smoke

View

Effect of Smoking Regime on Activated Carbon Desorption

View

Effect of Smoking Parameters on the Temperature in Cigarette Filters During Smoking

View

Draw Resistance During Smoking

View

Determination of Menthol in Cigarette Components by GC

View

Determination of Hoffmann Analytes in Cigarette Smoke

View

Determination of Amadori Compounds in Tobacco by Ion Pair Chromatography Coupled to Electrochemical Detector – the Latest Improvements

View

Detection of QTLs Linked to Leaf and Smoke Properties in Nicotiana Tabacum

View

Current Reliability of Measurements of Smoke Analytes

View

Current Measurement Reliability of Selected Smoke Analytes

View

The Risk Continuum

View

Plenary Presentation Building Trust – Science and Innovation

View

Limitations in the Characterisation of Cigarette Brands Using Different Machine Smoking Regimes

View

Determination of Selected Volatiles in Cigarette Smoke

View

Determination of Aromatic Amines in Cigarette Mainstream Smoke

View

ASR Yield Variability Under Different Regimes

View

Biological Test Procedure for Fresh Generated Smoke and Aerosols

View

Contribution of Near Infrared Spectrometry (NIRS) to Tobacco Breeding

View

Contribution of Genomic Research to Develop Disease Resistance in Tobacco

View

Construction of a Genetic Map of Nicotiana Tabacum

View

Compensation for the Effects of Ambient Conditions on the Calibration of Multi-Capillary Pressure Drop Standards pt2

View

Compensation for the Effects of Ambient Conditions on the Calibration of Multi-Capillary Pressure Drop Standards pt3

View

Compensation for the Effects of Ambient Conditions on the Calibration of Multi-Capillary Pressure Drop Standards

View

Comparison of Tobacco Extracts – A Strategy Based on GCXGC-MS Analysis and Chemometric Data processing

View

Comparison of Regular Smokers of Menthol and Non-Menthol Cigarettes on Smoking Profile and Exposure

View

Comparison of In Vitro Smoke Toxicity of Novel Charcoal Filter Cigarettes and Benchmark Cigarettes from the UK market

View

Comparison of Different Clean-Up Procedures for the Determination of Plant Protection Products in Tobacco and Tobacco Products by lC-MSMS

View

Chemical Changes in Cigarette Smoke Mutagenicity Associated with CMVPVY Infection in Burley Tobacco

View

Characterisation of the Draw Resistance Across a Lit Cigarette

View

Characterisation of PVY (Potato Virus Y) Resistance in Tobacco

View

Characterisation of French and Brazilian PVY Isolates from Susceptible or Resistant Tobacco Plants

View

Characterisation of Cigarette Hardness and Tobacco Filling Power

View

Cellular Transformation Activity of Different Tobacco Products in the Bhas42 Cell Assay

View

Building blu – Harm Reduction Science

View

Biological Test Procedure for Fresh Generated Smoke and Aerosols

View

Biological Assessment of Cigarette Whole Smoke

View

Assessment of Smokers’ T&N Yields

View

Assessment of Smokers’ T&N Yields Under Natural Smoking Conditions

View

Assessment of Flue-cured and Burley Breeding Progress in France

View

Applications of Near Infrared Reflectance Spectroscopy to Quantitative and Qualitative Characteristics of Tobacco Blends

View

Application of Near Infrared Spectroscopy to Tobacco Plant Breeding

View

Application of a Modal Reactor for Efficiency Testing of Potential Filter Additives

View

Application of 13C Tracer Technique to Study Fate and Behaviour of Ingredients Applied on Tobacco

View

Analysis of Pesticides in Tobacco by LC-MSMS Specific Matrix Effects on Quantification for Different Tobacco Grades

View

Analysis of 16 Amino Acids in Tobacco by Ion Pair LC ESI MS MS without Derivatisation

View

An Overview of Toxicity Testing in 21st Century (TT21C) – In Vitro Methods to Assess Next Generation Products

View

An International Survey of Indoor Air Quality, Ventilation and Smoking Activity in Restaurants

View

An Alternate Strategy of Risk Reduction for Tobacco Smokers

View

Airflow Characterisation within a Cigarette using a Permeability Meter

View

Agrobacterium T-DNA in N. tomentosiformis and other Nicotiana Species

View

A New Device for Firmness Characterisation

View

A Mixture Experimental Design with 6 Components and the Effects on Smoke Constituents

View

A Comprehensive Survey of the N. Tabacum Transcriptome

View