zone tobacco-free oral nicotine pouches contain high-purity pharmaceutical grade nicotine, usually sprayed onto a plant fibre-based substrate. These products are used by placing a pouch under the lip, releasing nicotine into the bloodstream via the gum lining (or oral mucosa).
The current scientific evidence suggests nicotine pouches are likely to be significantly less harmful for adult smokers than continuing to smoke because they:
- Neither contain or burn tobacco to release nicotine.
- Deliver nicotine through the gums rather than inhalation, meaning lung-related toxicity and disease risks are not to be expected.
Our zone oral nicotine pouches are understood by adult smokers and non-users alike to be, while not risk-free, potentially less harmful than cigarettes.
Levels of select harmful chemicals of public health interest in our high-quality nicotine pouch product, zone, are substantially lower compared to tobacco smoke.
In fact, the majority of the toxicants tested weren’t present in quantifiable levels.
With far fewer toxicants compared to cigarette smoke, zone nicotine pouches elicit much lower in-vitro toxicity compared to cigarettes with over 99% reduction in cytotoxicity, and no mutagenicity or genotoxicity produced under test conditions.
Further in-vitro testing shows they don't have skin sensitisation properties.
Our clinical research demonstrates zone nicotine pouches deliver nicotine to the blood of adult smokers, at a lower and slower rate than cigarettes, consistent with absorption via the oral mucosa.
However, our data also shows adult smokers find the product satisfying, reducing their desire to smoke.
Our zone oral nicotine pouches have a favourable short-term safety profile, with no serious adverse events reported during the period of our clinical research.
Tobacco harm reduction is cited as a reason why many adult smokers want to try or purchase zone nicotine pouches.
While zone is acceptable to adult smokers, they have very limited appeal among non-users.
This includes both younger and older never-users, as well as long-term adult smoker quitters.
For decades the idea has persisted that nicotine stains teeth.
Our research demonstrates it’s other chemicals found in cigarette smoke – created through the process of harmful tobacco combustion – that are responsible.
So, smoking cigarettes stains teeth but using zone tobacco-free oral nicotine pouches doesn’t.
